Curcumin induces apoptosis through the mitochondria-mediated apoptotic pathway in HT-29 cells
نویسندگان
چکیده
منابع مشابه
Curcumin Induces Apoptosis through Mitochondrial-mediated Apoptotic Pathway in Retinoblastoma Cells
Curcumin (diferuloylmethane), the main yellow bioactive component of turmeric has been shown to have wide variety of biological actions like anti-inflammatory, anticancer and antioxidant properties. Its anticancer effect is mainly mediated through induction of apoptosis. In the present study, we have investigated the effects of curcumin on growth and apoptosis in the human retinoblastoma (RB) c...
متن کاملCurcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway.
Osteosarcoma is one of the primary malignant bone tumors that confer low survival rates for patients even with intensive regime treatments. Therefore, discovery of novel anti-osteosarcoma drugs derived from natural products that are not harmful to the normal cells remains crucial. Curcumin is one of the natural substances that have been extensively studied due to its anti-cancer properties and ...
متن کاملPhloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells
Phloroglucinol is a polyphenolic compound that is used to treat and prevent several human diseases, as it exerts beneficial biological activities, including anti-oxidant, anti‑inflammatory and anticancer properties. The aim of the present study was to investigate the effects of phloroglucinol on apoptotic signaling pathways in HT-29 colon cancer cells. The results indicated that phloroglucinol ...
متن کاملPlumbagin induces the apoptosis of human tongue carcinoma cells through the mitochondria-mediated pathway
BACKGROUND Plumbagin, a quinonoid constituent isolated from the root of Plumbago zeylanica L., has been proven to possess anti-tumor activity both in vitro and in vivo. However, its anti-tumor properties for human tongue carcinoma have not been reported. This study aimed to investigate the inhibitory effect and the underlying mechanism of plumbagin on the growth of human tongue carcinoma cells....
متن کاملTaraxerol Induces Cell Apoptosis through A Mitochondria-Mediated Pathway in HeLa Cells
OBJECTIVES Taraxerol acetate has potent anti-cancer effects via the induction of apoptosis, autophagy, cell cycle arrest, and inhibition of cell migration. However, whether taraxerol induced apoptosis and its underlying mechanisms of action is not clear. In the present study, we assess the effects of taraxerol on the mitochondrial apoptotic pathway and determine the release of cytochrome c to t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Zhejiang University SCIENCE B
سال: 2009
ISSN: 1673-1581,1862-1783
DOI: 10.1631/jzus.b0820238